19 déc. 2013

TRIATHLON AND BIOLOGICAL PASSPORT III



Here we go again.  I thought this was over, but let´s go back to the subject now that Jonathan Tiernan-Locke was “caught” with the “Biological Passport violation.”  He was stopped from racing when he was losing; he was not finishing the races.  We are going to give you history regarding this cyclist and regarding what happened when you do not train well.  First we have what happened as incident:
In September, Tiernan-Locke had been asked by the sport's governing body to provide an explanation for irregularities in his biological passport, which are believed to date from late 2012 when he was racing for Endura, having agreed to join Team Sky for the following year.
A statement from the UCI read: "The analysis of the biological passport of Mr Jonathan Tiernan-Locke by the Experts Panel has demonstrated an anti-doping rule violation (use of prohibited substances and/or methods).
"Consequently and in compliance with the UCI anti-doping rules, the UCI has requested his National Federation to initiate disciplinary proceedings."
Andrew McQuaid, Tiernan-Locke's manager, released a statement on behalf of his rider, which read: "Jonathan Tiernan Locke was notified that the UCI wish to instruct British Cycling to instigate proceedings against him regarding an abnormality in his biological passport.
"Mr Tiernan Locke vehemently denies the charges brought against him and has informed the UCI that he fully intends to contest them. [He] is looking forward to a speedy and just resolution of these unfortunate charges."
In a separate statement, Team Sky confirmed that Tiernan-Locke would not ride or be involved in any team activities until a decision is made by doping authorities, and acknowledged that the abnormal readings pre-date his involvement with the team.
"We have been informed that he intends to defend himself against that charge," read the statement.
"There are no doubts about his approach or performance in Team Sky. This is a team that trains, races and wins clean."

I know what kind of EXPERT PANEL these International Unions have; panel made of friends except real experts.  It is dangerous to take decisions based on what they say.  We are falling into the Inquisition times if we continue this way.  I do not defend anyone regarding doping even less now that we know about doping in cycling, chances are that the 100% doping that it said that existed in the late 90´s is decreased; but not to zero, now it is closed to the latest percentage.

On our previous writings (posts), we said:
27 oct. 2013
I tackled a theme not too long ago: The Biological Passport.  It is necessary to speak clearly about it because bureaucrats want to be important like some of the referees in a Football game.  The biological passport is just a parameter to consider when evaluating doping in somebody.  Please see our post when the case of Mark Fretta came to light:
As we can see in the Hematopathology / Automated Blood Cell Counts Am J Clin Pathol 2008;130:104-116
It is also desirable that, as with the high standardization for basic CBC parameters, a continued effort be made for the parameters (ie, RDW, IRF, MCVr, and MPV) for which results provided are still too different when produced by different analyzers. To reach these goals, cooperation between long-standing (ie, International Council for Standardization in   Haematology and the National Committee for Clinical Laboratory Standards, now the Clinical and Laboratory Standards Institute) and recent (International Society of Laboratory Hematology) organizations interested in hematologic standardization and the manufacturers is fundamental. It should be remembered that despite the essential role of automation in the modern hematology laboratory, microscopic control of pathologic samples remains indispensable, so much so that in certain cases, it alone is diagnostic.134 Moreover, knowledge of the limits of the specific analyzer in use is of paramount importance for the correct interpretation of results. These considerations require that clinical laboratories performing hematologic diagnostics have personnel with specific training and profound knowledge in laboratory hematology.

We have to find the substance to make a case; otherwise, we are not beyond a reasonable doubt.  There is a criterion in the law that says: Beyond a Reasonable Doubt.
The standard that must be met by the prosecution's evidence in a criminal prosecution: that no other logical explanation can be derived from the facts except that the defendant committed the crime, thereby overcoming the presumption that a person is innocent until proven guilty.

Errors of measurement for blood volume parameters: a meta-analysis
Christopher J. Gore, Will G. Hopkins, Caroline M. Burger

Continuing with Jonathan, before the doping scandal, when he was not finishing the races:
After a long break from racing, Jonathan Tiernan Locke returned to competition on Sunday in the Vattenfalls Cyclassics, the first step in what he hopes will be a successful attempt to turn around a difficult season… “It has been a bit more complicated, in terms of stepping up to the WorldTour. It’s been an issue with handling the training load, more than anything," he told VeloNation recently.

“Last year I had pretty much only myself to worry about and when we got to races, if it was a hilly race, I would get a free rein. This year I have been riding for guys of the calibre of Richie Porte and Chris Froome. So it has also been about learning, but also about trying to adapt to the different training and having a programme set out for me. In the past, I always just looked after my own training and came up my own plan.”  Essentially, he’s gone from riding on feel to this year training to a structured programme. It’s something that hasn’t worked out as hoped. “Before, if I was tired, I would just take the day off. So that has been different.”

The team’s training works well for other riders and so it’s relevant to determine why Tiernan Locke is different. Does he believe his physiology needs an alternative approach to some of the other riders, or is it the case that the step up to the WorldTour is what has posed the problem?

“I believe it is the former, to be honest,” he answered. “I got to mid-July and I was just knackered. I saw my performances going down and down…I was getting progressively more fatigued… Whereas myself, I find if I train too much it comes back at me. I have done it in the past, training myself and looking for a bit more…you always think, ‘I am going well now, so if I keep pushing and pushing I should build up,’ but I don’t respond well to that. Past a certain point, I seem to just go downhill and need to rest to come out of it.”
It is obvious that he was not made yet for this kind of training regime:
After a desperate month he returned to the UK, giving up the sport entirely. He became a rider lost: dropped from the sphere of competitive racing, an athlete unable to cut it at the top, and who despite all their promise, one who failed to make it in the big leagues.

“I turned my back on the sport. I went to university and thought about another career. I put on two stone, drank, partied and didn’t touch my bike. Keeping active for me was walking home from the pub totally pissed.”
For three years Locke didn’t even look at a bike. Then, in 2008, towards the end of his studies a friend offered him a part time position in a local bike shop. The majority of his university funds had financed his rampant partying, and so the proposition of cash and paying back student fees was too much to turn down.
His stint at the bike shop coincided with the Tour de France and each day the shop would show the day’s action on television. Both colleagues and customers would stand around and watch as the action played out each day and cries of ‘great stage’, ‘what an attack’ would flow as they dissipated from the television screen and back to their regular business.

Training changes the biology of our body if we are not used to hard work, huge training volumes, and order in our routines for recovery and nutrition as pointed out in the following article.  Real anemia and other hematological changes are seen rapidly in these subjects.  He was winning in 2012 and things changed drastically in 2013 when training with Team Sky.  We have seen it in some of our athletes:
Oxidative stress during rehabilitation from protein malnutrition associated with aerobic exercise in rats

It has also been suggested that kwashiorkor, a severe form of protein malnutrition, may itself be a product of the radical initiated tissue damage in the malnourished child (Golden and Ramdath, 1987; Manary et al., 2000). The present study was designed to evaluate biomarkers of oxidative stress, nutritional status and muscle metabolism in rats submitted or not to exercise during a month recovery from protein malnutrition.

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